Thyroid Peroxidase Antibody (Anti-TPO), Serum Test Overview

What is the Thyroid Peroxidase Antibody, Serum Test?

The Thyroid Peroxidase Antibody (TPOAb) test measures the level of antibodies directed against the enzyme thyroid peroxidase — a crucial component in the production of thyroid hormones. When your immune system mistakenly attacks this enzyme, it can lead to inflammation and damage of the thyroid gland, often resulting in conditions like Hashimoto’s thyroiditis or Graves’ disease.

This test helps diagnose autoimmune thyroid disorders and can also be used to monitor their progression. High levels of TPO antibodies are often found in individuals with hypothyroidism or hyperthyroidism and may appear even before symptoms develop. Common signs suggesting thyroid dysfunction include fatigue, unexplained weight changes, sensitivity to cold or heat, hair loss, or irregular menstrual cycles.

Understanding TPO antibody levels is important because early detection of autoimmune thyroid disease allows for timely management, helping to prevent long-term complications such as goiter, infertility, or heart problems. Your doctor may recommend this test if you show thyroid-related symptoms, have a family history of thyroid disorders, or are undergoing thyroid treatment.

Why Take the Thyroid Peroxidase Antibody, Serum Test?

This test is recommended if you:

• Have symptoms of thyroid dysfunction such as fatigue, weight changes, or mood swings

• Have a family history of autoimmune thyroid disease

• Are diagnosed with hypothyroidism or hyperthyroidism to identify the cause

• Are pregnant or planning a pregnancy, as autoimmune thyroid conditions can affect pregnancy outcomes

• Are being monitored for autoimmune diseases such as lupus or rheumatoid arthritis

How is the Thyroid Peroxidase Antibody, Serum Test Carried Out?

A small blood sample is drawn from a vein in your arm. The sample is then analyzed in the laboratory to detect the presence and level of thyroid peroxidase antibodies. The process is quick, safe, and minimally uncomfortable, and results are usually available within a few hours.

How do I Prepare for the Thyroid Peroxidase Antibody, Serum Test?

• Diet: No fasting or dietary restrictions are required.

• Activity: Continue your usual routine.

• Medications: Inform your doctor if you are taking thyroid medication, steroids, or immunosuppressants, as they may affect results.

Next Steps

If your TPO antibody levels are elevated, your doctor may:

• Recommend additional thyroid tests (TSH, Free T4, or Free T3) to assess thyroid function

• Monitor your thyroid health over time, especially if you have mild or early-stage autoimmune thyroid disease

• Suggest lifestyle and dietary changes to support thyroid health

• Prescribe medication if thyroid hormone levels are abnormal

If results are normal but symptoms persist, further evaluation may be done to rule out other causes of thyroid dysfunction.

Why Choose Docty Labs?

✅ NABL-Certified Testing Centres
✅ On-time, Accurate Reports
✅ 100% Digital Reports Available
✅ Affordable Lab Tests & Membership Discounts
✅ Hygienic, Safe, and Convenient Home Sample Collection
✅ Free Teleconsultation with Experienced Doctors from Docty Clinics
✅ Trusted by Doctors and Families Across India

Frequently Asked Questions (FAQs)

• What is the Thyroid Peroxidase Antibody Test?
  It measures antibodies that target the thyroid peroxidase enzyme, helping detect autoimmune thyroid disorders.

• Is fasting required for this test?
  No, fasting is not required. You can eat and drink normally before the test.

• Can high TPO antibodies exist without thyroid symptoms?
  Yes, elevated antibodies can appear before thyroid dysfunction develops, indicating a risk for future issues.

• Can this test diagnose all thyroid diseases?
  No, it specifically detects autoimmune-related thyroid conditions. Additional thyroid function tests may be needed.

• How long will it take to get my report?
  Reports are usually ready within 4 hours.

• Is this test available for home collection?
  Yes, Docty Labs offers safe and convenient home blood sample collection.

• Does Docty offer discounts on thyroid tests?
  Yes, members receive additional discounts on lab tests and packages.

• How can I book the Thyroid Peroxidase Antibody Test?
  You can book online by selecting “Add to Cart” or visit/call your nearest Docty Lab. Home collection is available in Hyderabad.