Sex Hormone Binding Globulin (SHBG), Serum Test Overview

What is the Sex Hormone Binding Globulin (SHBG), Serum Test?

The Sex Hormone Binding Globulin (SHBG), Serum Test measures the level of SHBG in your blood — a protein produced by the liver that binds to sex hormones like testosterone and estrogen. SHBG helps regulate how much of these hormones are freely available to your body’s tissues.

Abnormal SHBG levels can disrupt the balance of active hormones, leading to symptoms related to either hormone excess or deficiency. High SHBG levels may be seen in conditions such as hyperthyroidism, liver disease, or low androgen production, while low SHBG levels can occur in obesity, type 2 diabetes, hypothyroidism, and polycystic ovary syndrome (PCOS).

This test helps doctors better interpret total testosterone or estrogen results by determining how much hormone is biologically active. It is especially useful for assessing fertility issues, menstrual irregularities, reduced libido, or symptoms of hormonal imbalance in both men and women. Identifying abnormal SHBG levels enables more accurate diagnosis and targeted treatment for underlying conditions affecting hormone balance.

Why Take the Sex Hormone Binding Globulin (SHBG), Serum Test?

This test is recommended if you:

• Have symptoms of hormone imbalance, such as fatigue, reduced libido, or mood changes

• Are being evaluated for infertility, menstrual irregularities, or PCOS

• Have abnormal testosterone or estrogen levels and need further clarification

• Are experiencing signs of excessive androgen activity, such as acne or hair loss

• Have liver disease, thyroid disorders, or metabolic syndrome that may affect hormone regulation

How is the Sex Hormone Binding Globulin (SHBG), Serum Test Carried Out?

• A small blood sample is collected from a vein in your arm.

• The sample is processed in the laboratory to measure SHBG concentration using precise analytical methods.

• The results are interpreted alongside other hormone tests like total and free testosterone or estradiol.

How do I Prepare for the Sex Hormone Binding Globulin (SHBG), Serum Test?

• Fasting: Not required.

• Medications: Inform your doctor about any hormone therapies, steroids, or birth control pills you are taking, as they can affect results.

• Lifestyle: Avoid intense exercise or alcohol before the test, as these can temporarily influence hormone levels.

Next Steps

If SHBG levels are abnormal, your doctor may:

• Recommend additional tests such as total testosterone, free testosterone, or estradiol

• Evaluate for underlying conditions like thyroid disorders, liver disease, or PCOS

• Adjust medications or hormone therapy as needed

• Suggest lifestyle changes, including weight management or dietary adjustment,s to restore hormone balance

Why Choose Docty Labs?

✅ NABL-Certified Testing Centres
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✅ Hygienic, Safe, and Convenient Home Sample Collection
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Frequently Asked Questions (FAQs)

• What does the SHBG test measure?
  It measures the level of Sex Hormone Binding Globulin in your blood, which affects the availability of testosterone and estrogen.

• Do I need to fast before the test?
  No fasting is required. However, follow your doctor’s advice if you are on hormone-related medication.

• Who should take this test?
  Men and women with symptoms of hormonal imbalance, fertility problems, or irregular menstrual cycles.

• Can I take this test at home?
  Yes, Docty Labs provides safe and convenient home blood sample collection.

• Is the test safe?
  Yes, it involves a simple blood draw and carries minimal risk.

• When will I get my results?
  Results are usually available within 6 hours.

• Does Docty offer discounts on this test?
  Yes, Docty Labs provides additional discounts for members under its annual health plans.

• How can I book the SHBG, Serum Test?
  You can book online by selecting “Add to Cart” or contact your nearest Docty Lab. Home collection is available in Hyderabad.