Metanephrines, 24 Hrs Urine Test Overview

What is the Metanephrines, 24 Hours Urine Test?

The Metanephrines, 24 Hours Urine Test measures the amount of metanephrines—breakdown products of adrenaline (epinephrine) and noradrenaline (norepinephrine)—excreted in your urine over a full day. These hormones are produced by the adrenal glands and play a key role in managing the body’s stress response.

This test helps detect pheochromocytoma and paraganglioma, rare tumors of the adrenal glands that can cause excessive hormone release. Symptoms such as persistent high blood pressure, severe headaches, palpitations, sweating, and anxiety may indicate the need for this test.

High levels of urinary metanephrines can suggest overactive adrenal glands or related tumors, while normal levels usually rule out these conditions. Measuring metanephrines over 24 hours gives a more accurate picture than a single urine sample, since hormone secretion can fluctuate throughout the day.

By identifying abnormal hormone activity early, this test helps doctors prevent serious complications such as uncontrolled hypertension or cardiovascular issues. It’s an essential diagnostic step for anyone experiencing unexplained high blood pressure, anxiety-like episodes, or other symptoms of excess adrenaline.

Why Take the Metanephrines, 24 Hours Urine Test?

This test is recommended if you:

• Have symptoms such as high blood pressure, headaches, or excessive sweating

• Experience anxiety or a rapid heartbeat without an apparent cause

• Are being evaluated for adrenal gland or neuroendocrine tumors

• Have a family history of pheochromocytoma or paraganglioma

• Need monitoring for recurrence after treatment of adrenal tumors

How is the Metanephrines, 24 Hours Urine Test Carried Out?

• Collect all urine over a 24-hour period in a special container provided by the lab.

• Discard the first urine of the day, then collect all urine for the next 24 hours, including the first sample on the following morning.

• Store the container in a cool place during collection and return it to the lab once complete.

How do I Prepare for the Metanephrines, 24 Hours Urine Test?

• Diet: Avoid coffee, tea, alcohol, chocolate, vanilla, and bananas for 2–3 days before and during sample collection.

• Activity: Try to stay calm and avoid physical or emotional stress during the collection period.

• Medications: Inform your doctor about all medications, especially antidepressants, blood pressure medicines, or nasal sprays, as they can affect results.

Next Steps

If results indicate elevated metanephrines, your doctor may:

• Recommend imaging tests (CT or MRI) to detect adrenal tumors

• Adjust medications that might be influencing hormone levels

• Suggest surgical or medical treatment for confirmed tumors

• Continue regular monitoring to prevent recurrence or complications

Why Choose Docty Labs?

✅ NABL-Certified Testing Centres
✅ On-time, Accurate Reports
✅ 100% Digital Reports Available
✅ Affordable Lab Tests & Membership Discounts
✅ Hygienic, Safe, and Convenient Home Sample Collection
✅ Free Teleconsultation with Experienced Doctors from Docty Clinics
✅ Trusted by Doctors and Families Across India

Frequently Asked Questions (FAQs)

• What is the Metanephrines, 24 Hours Urine Test?
  It measures metanephrine and normetanephrine levels in urine to detect adrenal gland tumors like pheochromocytoma.

• Is fasting required?
  Fasting is not necessary, but certain foods and drinks should be avoided for 2–3 days before the test.

• Can the test be done at home?
  Yes, Docty Labs provides containers and guidance for safe home urine collection.

• Is the test safe?
  Yes, it is completely non-invasive and safe when done with proper instructions.

• How soon will I get results?
  Reports are usually available within 24 hours.

• Does Docty offer discounts?
  Docty Labs offer an additional 20% discount on labs with an annual membership plan.

• How can I book the Test?
  Book online by clicking “Add to Cart” or call your nearest Docty Lab. Home collection is available in Hyderabad.